Dylan O'Brien originally went in to the auditions to read for the role of Scott but felt a better connection to the role of Stiles.
When Dylan O'Brien auditioned he brought a blank piece of paper and a link to two of his YouTube videos.
Orny Adams (Coach) revealed at the nine year reunion that he didn't read any of the full scripts after sometime in season two; he figured Coach wasn't supposed to know any of what was going on anyway.
Many of the supposed wolf howls heard on the show are actually gorillas.
According to creator Jeff Davis,The Lost Boys (1987), Buffy the Vampire Slayer (1997) and the Spider-Man comics were huge influences on creating this series.